Our analysis showed that the staff of the prescribing physicians' practices had great difficulty in dealing professionally with the non-adherence of patients. Instead of supporting the patients throughout the therapy, the patients were reproached. As a counter-measure, we designed a training concept that enabled the practice staff to improve patient adherence by using suitable communication tools. Another measure was to make communication with the patients more empathic and appreciative. Due to the close reference to indications, such a seminar concept can be implemented in compliance with the codex (FSA).